Effects of experimental <i>Trichinella spiralis</i> larvae infection in rats and mice on hematological and biochemical parameters of the host at different infection stages

The purpose of the research is study effects experimental Trichinella spiralis infection in rats and mice on hematological biochemical blood parameters host at different stages. Materials methods . experiment was performed mature outbred male that were infected by T. larvae orally administered rate 10 larvae/1 g body weight. Blood samples taken from 40 days 3 months after infection; mice, day infection. main peripheral determined a MicroCC-20 Plus analyzer (High Technology, Inc. (USA)) using reagents Clinical Diagnostic Solutions, LLC (Russia). Biochemical Clima MC-15 analyzer, RAL Technical el Laboratoria, S.A. (Spain) produced Diakon-DS, CJSC Results discussion At experimentally with , we observed consistent increase hemoglobin concentration, erythrocytes leukocytes, hematocrit, decrease alkaline phosphatase activity ALT, an total protein. On protein as rats, urea. changes detected associated toxic effect response organism. Such are dependent stage animal species.